如何改善卵母细胞质量

发布时间：2018-05-26 08:18

本文选题：卵母细胞质量 + 线粒体　；参考：《生殖医学杂志》2015年10期

【摘要】：卵母细胞质量是直接影响反复种植失败和反复流产患者妊娠结局的主要因素,这类患者若要获得成功妊娠,关键在于改善卵母细胞质量。卵母细胞质量主要与高龄、超排卵、免疫、代谢、遗传等因素相关,其中,卵母细胞线粒体在卵母细胞减数分裂和胞浆成熟的作用尤其受到关注。改善卵母细胞质量主要通过增加线粒体数量和改善线粒体功能,近年来发展的自体生殖系干细胞线粒体移植以及卵巢组织体外激活为临床实践和研究提供了新方向。
[Abstract]:The quality of oocytes is the main factor that directly affects the pregnancy outcome of patients with repeated implantation failure and repeated abortion. If these patients want to obtain successful pregnancy, the key is to improve the quality of oocytes. The quality of oocytes is mainly related to aging, superovulation, immunity, metabolism and heredity, among which the role of oocyte mitochondria in oocyte meiosis and cytoplasmic maturation is of particular concern. Improving the quality of oocytes mainly by increasing the number of mitochondria and improving the function of mitochondria. In recent years, mitochondrial transplantation of autologous reproductive stem cells and activation of ovarian tissue in vitro provide a new direction for clinical practice and research.
【作者单位】：中山大学附属第一医院生殖医学中心;
【分类号】：R321

【共引文献】