鲍曼不动杆菌院内感染临床分布特征及耐药率变迁分析

发布时间：2018-12-20 13:05

【摘要】：目的分析鲍曼不动杆菌院内感染的临床分布特征及耐药率变迁，，为临床合理用药提供参考，减少细菌耐药及提高清除率。方法收集病原学培养结果为鲍曼不动杆菌感染的住院患者临床资料,总结分析临床分布特点；比较不同年度、不同科室菌株的耐药率差别。结果558株鲍曼不动杆菌标本来源中痰所占比例最高，达70.07%。重症监护病房和烧伤科分离率最高。来自于ICU科室的菌株耐药率较非ICU科室高。2007-2013本院耐药率变化中，头孢哌酮舒巴坦的耐药率每年最低，整体耐药率略高于全国CHINET监测水平。结论ICU病房鲍曼不动杆菌分离率和耐药率高；分离出多重耐药菌株的患者同期混合感染比例高。头孢哌酮舒巴坦耐药率最低，可作为感染的临床首选药物。
[Abstract]:Objective to analyze the clinical distribution and drug resistance rate of Acinetobacter baumannii nosocomial infection in order to provide reference for rational drug use, reduce bacterial resistance and improve clearance rate. Methods the clinical data of the inpatients infected with Acinetobacter baumannii were collected and the clinical distribution characteristics were analyzed. Results the percentage of sputum in 558 strains of Acinetobacter baumannii was the highest (70.07%). The isolation rate of intensive care unit and burn department was the highest. The drug resistance rate of the strains from the ICU department was higher than that from the non-ICU department. The resistance rate of cefoperazone sulbactam was the lowest every year and the overall drug resistance rate was slightly higher than that of the national CHINET monitoring level in the change of drug resistance rate in our hospital from 2007 to 2013. Conclusion the isolation rate and drug resistance rate of Acinetobacter baumannii were high in ICU ward, and the rate of mixed infection was higher in patients with multiple drug resistance strains. Cefoperazone sulbactam has the lowest resistance rate and can be used as the first choice for infection.
【学位授予单位】：广西医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R378

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