中国人群主动脉根部结构及生理影响因素研究
发布时间：2019-05-18 06:57
【摘要】： 研究目的和意义:探讨性别、年龄、身高、体重、体表指数BMI、体表面积BSA、收缩压、舒张压及脉压等生理因素对中国人群主动脉窦部、环部及弓部结构的影响。 研究内容和方法: 1.重复性研究 入选2007年9月至12月盐城市第一人民医院住院病人共11例,排除标准:扩张性心肌病,肥厚性心肌病,心肌炎,先天性心脏病,主动脉瓣膜病变,主动脉窦瘤,主动脉缩窄,主动脉弓部畸形及主动脉瓣置换术后病人均不在入选范围之内。通过PHILIP - 7500型彩色多普勒显像仪二维超声测量主动脉瓣环部、窦部及弓部的内径。同一名检测医生在不同时间段先后三次,对11名受试者进行测量。三名检测医生在不同时间段,各自分别对11名受试者进行测量。 由SPSS13.0软件包进行重复试验的信度和内部相关一致性进行检验。 2.相关性研究 入选2007年9月至12月盐城市第一人民医院住院病人共748例,排除标准:扩张性心肌病,肥厚性心肌病,心肌炎,先天性心脏病,主动脉瓣膜病变,主动脉窦瘤,主动脉缩窄,主动脉弓部畸形及主动脉瓣置换术后病人均不在入选范围之内。有效数据715例,有效比例95.6%。 通过PHILIP - 7500型彩色多普勒显像仪对受试者进行二维超声测量主动脉瓣环部、窦部及弓部的内径,并且记录受试者性别、身高、体重、体表指数BMI、体表面积BSA、收缩压、舒张压及脉压。每个对象测量3次,每次测量都在ECG同一位置进行超声图象存档,相关软件进行测量分析记录。 由SPSS13.0软件包采用多元逐步回归法分析得出相关因素及其回归方程,并作出散点图。 研究结果: 1.与主动脉窦部直径关系最重要的因素是年龄,其次是体表面积BSA、性别、和舒张压,其中与性别负相关。回归方程为窦=17.148+4.553XBSA+0.056X年龄-1.276X性别+0.027X舒张压 2.与主动脉环部直径关系最重要的因素是体表面积BSA,其次是性别、年龄,其中与性别负相关。回归方程为环=12.565+4.690XBSA-1.053X性别+0.022X年龄 3.与主动脉弓部直径关系的因素是年龄和体表面积BSA。回归方程为弓=13.645+4.694XBSA+0.051X年龄 结论: 1.主动脉窦部,瓣环及弓部直径有显著的性别差异,在窦部及环部可以用性别引起的体表面积差异解释,但弓部尚不能用性别引起的体表面积差异解释。 2.体表面积是主动脉窦部,瓣环部及弓部结构重要影响因素。随着体表面积增加而升高。体表面积是影响主动脉环部直径大小最重要的影响因素。 3.年龄是主动脉窦部,瓣环部及弓部重要影响因素。随着年龄增长而扩大。年龄是影响主动脉窦部及弓部直径大小最重要的影响因素 4.主动脉窦部直径大小随着舒张压升高而升高。舒张压是一个相对次要的影响因素。
[Abstract]:Objective and significance: to investigate the effects of physiological factors such as sex, age, height, weight, body surface index BMI, body surface area BSA, systolic blood pressure, diastolic blood pressure and pulse pressure on aortic sinus, ring and arch structure in Chinese population. Research contents and methods: 1. From September to December 2007, 11 inpatients in Yancheng first people's Hospital were enrolled in the repetitive study. The exclusion criteria were dilated cardiomyopathy, hypertrophic cardiomyopathy, myocarditis, congenital heart disease and aortic valvular disease. Aortic sinus aneurysm, aortic coarctation, aortic arch malformation and aortic valve replacement were not included. The inner diameters of aortic valve ring, sinus and arch were measured by PHILIP-7500 color Doppler imaging. The same examiner measured 11 subjects three times in different periods. The three doctors measured 11 subjects at different time periods. The reliability and internal consistency of repeated tests were tested by SPSS13.0 software package. 2. A total of 748 inpatients in Yancheng first people's Hospital from September to December 2007 were enrolled in the study. The exclusion criteria were dilated cardiomyopathy, hypertrophic cardiomyopathy, myocarditis, congenital heart disease and aortic valvular disease. Aortic sinus aneurysm, aortic coarctation, aortic arch malformation and aortic valve replacement were not included. The effective data were 715 cases, the effective rate was 95.6%. The inner diameters of aortic annulus, sinus and arch were measured by two-dimensional ultrasound with PHILIP-7500 color Doppler imager. the gender, height, weight and body surface index BMI, surface area BSA, systolic blood pressure were recorded. Diastolic pressure and pulse pressure. Each object was measured three times, and the ultrasonic image was archived in the same location of ECG, and the related software was used for measurement and analysis. By using SPSS13.0 software package, the related factors and their regression equations are analyzed by multivariate stepwise regression method, and the scattered point diagram is made. Results: 1. The most important factor related to aortic sinus diameter was age, followed by body surface area BSA, sex and diastolic blood pressure, which was negatively correlated with sex. The regression equation was sinus = 17.148 4.553XBSA 0.056X age-1.276X sex 0.027X diastolic blood pressure. The most important factor related to the diameter of aortic ring was that body surface area BSA, was followed by sex and age, which was negatively correlated with sex. The regression equation is ring = 12.565 4.690XBSA-1.053X sex 0.022X age. The factors related to the diameter of aortic arch are age and body surface area BSA.. The regression equation is arch = 13.645 4.694XBSA 0.051X age conclusion: 1. There was significant gender difference in the diameter of aortic sinus, valvular ring and arch. The difference of body surface area caused by sex could be explained in sinus and ring, but the difference of body surface area caused by sex could not be explained in arch. 2. Body surface area is an important factor affecting the structure of aortic sinus, valve ring and arch. It increases with the increase of body surface area. Body surface area is the most important factor affecting the diameter of aortic ring. 3. Age is an important influencing factor in aortic sinus, valvular ring and arch. It expands with age. Age is the most important factor affecting the diameter of aortic sinus and arch. The diameter of aortic sinus increased with the increase of diastolic pressure. Diastolic blood pressure is a relatively secondary factor.
【学位授予单位】：苏州大学
【学位级别】：硕士
【学位授予年份】：2008
【分类号】：R33
本文编号：2479772
[Abstract]:Objective and significance: to investigate the effects of physiological factors such as sex, age, height, weight, body surface index BMI, body surface area BSA, systolic blood pressure, diastolic blood pressure and pulse pressure on aortic sinus, ring and arch structure in Chinese population. Research contents and methods: 1. From September to December 2007, 11 inpatients in Yancheng first people's Hospital were enrolled in the repetitive study. The exclusion criteria were dilated cardiomyopathy, hypertrophic cardiomyopathy, myocarditis, congenital heart disease and aortic valvular disease. Aortic sinus aneurysm, aortic coarctation, aortic arch malformation and aortic valve replacement were not included. The inner diameters of aortic valve ring, sinus and arch were measured by PHILIP-7500 color Doppler imaging. The same examiner measured 11 subjects three times in different periods. The three doctors measured 11 subjects at different time periods. The reliability and internal consistency of repeated tests were tested by SPSS13.0 software package. 2. A total of 748 inpatients in Yancheng first people's Hospital from September to December 2007 were enrolled in the study. The exclusion criteria were dilated cardiomyopathy, hypertrophic cardiomyopathy, myocarditis, congenital heart disease and aortic valvular disease. Aortic sinus aneurysm, aortic coarctation, aortic arch malformation and aortic valve replacement were not included. The effective data were 715 cases, the effective rate was 95.6%. The inner diameters of aortic annulus, sinus and arch were measured by two-dimensional ultrasound with PHILIP-7500 color Doppler imager. the gender, height, weight and body surface index BMI, surface area BSA, systolic blood pressure were recorded. Diastolic pressure and pulse pressure. Each object was measured three times, and the ultrasonic image was archived in the same location of ECG, and the related software was used for measurement and analysis. By using SPSS13.0 software package, the related factors and their regression equations are analyzed by multivariate stepwise regression method, and the scattered point diagram is made. Results: 1. The most important factor related to aortic sinus diameter was age, followed by body surface area BSA, sex and diastolic blood pressure, which was negatively correlated with sex. The regression equation was sinus = 17.148 4.553XBSA 0.056X age-1.276X sex 0.027X diastolic blood pressure. The most important factor related to the diameter of aortic ring was that body surface area BSA, was followed by sex and age, which was negatively correlated with sex. The regression equation is ring = 12.565 4.690XBSA-1.053X sex 0.022X age. The factors related to the diameter of aortic arch are age and body surface area BSA.. The regression equation is arch = 13.645 4.694XBSA 0.051X age conclusion: 1. There was significant gender difference in the diameter of aortic sinus, valvular ring and arch. The difference of body surface area caused by sex could be explained in sinus and ring, but the difference of body surface area caused by sex could not be explained in arch. 2. Body surface area is an important factor affecting the structure of aortic sinus, valve ring and arch. It increases with the increase of body surface area. Body surface area is the most important factor affecting the diameter of aortic ring. 3. Age is an important influencing factor in aortic sinus, valvular ring and arch. It expands with age. Age is the most important factor affecting the diameter of aortic sinus and arch. The diameter of aortic sinus increased with the increase of diastolic pressure. Diastolic blood pressure is a relatively secondary factor.
【学位授予单位】：苏州大学
【学位级别】：硕士
【学位授予年份】：2008
【分类号】：R33
【参考文献】
相关期刊论文 前1条
1 孙明,魏静义,陈保俊,李敏;主动脉根部外科解剖及其与毗邻结构关系[J];中华胸心血管外科杂志;2002年06期
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