冠状动脉多支重度病变患者左房容量及功能的三维研究

发布时间：2018-02-02 19:57

本文关键词： 超声冠状动脉多支病变左心房功能　出处：《新疆医科大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:应用实时三维超声心动图(real time three dimensional echocardiography,RT-3DE)评价冠状动脉多支重度狭窄患者左心房容量及功能变化?方法:根据冠状动脉造影结果选取冠脉单支重度病变患者31例?冠脉多支重度病变患者48例和对照组29例?三组均行三维超声心动图检查,测量左心房最小容积(LAVmin)、左心房最大容积(LAVmax)及左心房收缩前容积(LAVpre),左心房总排空容积(LAVt)?左心房总射血分数(LAVtEF)?左心房被动排空容积(LAVp)?左心房被动排空分数(LAVpEF)?左心房主动排空容积(LAVa)?左心房主动排空分数(LAVaEF)?左心房功能指数(LAFI)及左心室流出道时间速度积分(LVOT-VTI)?结果:与对照组相比,冠状动脉单支重度病变组LAVpEF指标显著降低,其余指标两组间差异无统计学意义;冠状动脉多支重度病变组较其他两组LAVpEF和LAFI降低?LAVpre增高,并且LAVa显著高于对照组(P0.05)?受试者工作特征曲线(ROC)分析显示左心房各功能参数中LAVpEF诊断冠状动脉重度病变的曲线下面积最大,最佳截断值、曲线下面积、敏感性及特异性分别为0.50、0.864?93.7%?72.4%。结论:冠状动脉重度病变影响左心房功能变化:管道功能反映左心房功能早期变化并随着冠脉病变支数增多受损程度进一步加重,冠脉多支重度病变下助力泵功能可代偿性增强。我们推测LAVpEF可能是检测冠状动脉重度病变的最佳评价指标。
[Abstract]:Objective: to use real time three dimensional echocardiography in real-time three-dimensional echocardiography. RT-3DEV was used to evaluate the changes of left atrial volume and function in patients with severe coronary artery stenosis. Methods: according to the results of coronary angiography, 31 patients with severe coronary artery disease were selected. There were 48 patients with severe coronary artery disease and 29 patients in control group. Three dimensional echocardiography was performed in all the three groups. The minimum volume of left atrium (LAVmin), the maximal volume of left atrium (LAVmax.) and the volume of left atrial presystolic volume (LAVprep) were measured. Left atrial total emptying volume? Left atrial total ejection fraction? Left atrium passive emptying volume? Left atrium passive emptying fraction (LAVpEFV)? Left atrium active emptying volume? Left atrium active emptying fraction LAVaEFA? Left atrial function index (Lafi) and left ventricular outflow tract time velocity (LVOT-VTI)? Results: compared with the control group, the LAVpEF index in the patients with severe coronary artery disease was significantly lower than that in the control group, but there was no significant difference between the other two groups. Compared with the other two groups, the LAVpEF and LAFI in the patients with severe coronary artery disease were lower than those in the other two groups. LAVpre was increased and LAVa was significantly higher than that of control group (P 0.05). The analysis of operating characteristic curve showed that the area under the curve of LAVpEF in diagnosing severe coronary artery disease was the largest, the best truncation value and the area under curve were the highest among all the functional parameters of left atrium. The sensitivity and specificity were 0.50 ~ 0.864? 93.7cm? Conclusion: the changes of left atrial function are affected by severe coronary artery disease: the function of conduit reflects the early changes of left atrial function and the degree of damage is further aggravated with the increase of coronary artery disease branches. We speculate that LAVpEF may be the best index to evaluate the severity of coronary artery disease.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R541.4

【相似文献】