吸烟与冠心病合并高血压患者血同型半胱氨酸及白细胞水平之间的关系

发布时间：2018-02-13 17:38

  本文关键词： 冠状动脉硬化型心脏病 高血压病 同型半胱氨酸 白细胞　出处：《医学与哲学(B)》2017年04期 　论文类型：期刊论文

【摘要】：探讨分析吸烟与高血压病(HTN)合并冠心病(CAD)患者血同型半胱氨酸(Hcy)及白细胞(WBC)计数水平之间的关系。选择CAD合并HTN患者148例,HTN患者179例,测定血Hcy、WBC、血脂水平等指标,分析CAD+HTN组与HTN组病例间不同吸烟状况对血Hcy、WBC、血脂水平的影响。在各项检查指标中,同型半胱氨酸(Hcy)、总胆固醇(TC)、甘油三酯(TG)和低密度脂蛋白(LDL-C)在两组之间有显著性差异(P0.05)。吸烟使高血压患者血Hcy、WBC、血脂水平升高,这也可能是吸烟促进HTN患者CAD发生发展的关键机制,可作为HTN患者CAD发展程度的判定指标,为早期诊断、预防和控制HTN合并CAD的发生和发展提供参考。
[Abstract]:To explore the relationship between smoking and serum homocysteine (Hcy) and white blood cell count (WBC) in patients with hypertension (HTN) and coronary heart disease (CAD). To analyze the influence of different smoking status between CAD HTN group and HTN group on the blood Hcyn WBC, blood lipid level. There was a significant difference between the two groups in homocysteine, total cholesterol, triglyceride and low density lipoprotein (LDL-C). Smoking increased the level of serum Hcyn WBC and blood lipids in patients with hypertension, which may also be the key mechanism of smoking to promote the development of CAD in patients with HTN. It can be used as an index to judge the development of CAD in patients with HTN, and to provide a reference for early diagnosis, prevention and control of the occurrence and development of HTN combined with CAD.
【作者单位】： 大连医科大学附属第一医院心血管检查科;
【分类号】：R541.4;R544.1
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本文编号：1508718