应用分层应变技术评估Ⅱ型糖尿病及糖耐量异常患者左心室各层心肌收缩功能改变

发布时间：2018-02-24 15:35

本文关键词： 分层应变超声心动图 Ⅱ型糖尿病糖耐量异常　出处：《中国超声医学杂志》2017年01期 　论文类型：期刊论文

【摘要】：目的应用分层应变技术评估Ⅱ型糖尿病患者及糖耐量异常患者左心室各层心肌收缩功能的改变。方法对38例Ⅱ型糖尿病、40例糖耐量异常患者和36例正常对照者进行常规超声心动图测量,存储二维动态图像后在EchoPAC工作站进行描记分析,获得左室壁18个节段的内、中层及外层心肌的收缩期峰值圆周应变(CS)、收缩期峰值纵向应变(LPS)及整体的分层和全层应变值。结果左室整体内、中、外层及整体全层CS在3组之间的差异有统计学意义(P0.05),整体内、中层和整体LPS在3组之间的差异有统计学意义(P0.05),整体外层LPS在3组之间的差异无统计学意义(P0.05);基底段内、中、外层,中间段内、中、外层CS在3组之间的差异有统计学意义(P0.05),基底段内、中、外层,中间段内、中层LPS在3组之间的差异有统计学意义(P0.05),心尖段三层心肌CS、LPS及中段外层心肌LPS在3组之间的差异无统计学意义(P0.05)。结论分层应变技术可定量评价糖尿病及糖耐量异常患者左心室各层及整体心肌的收缩功能改变,对于评价糖尿病及糖耐量异常患者左心室早期改变具有一定的临床应用价值。
[Abstract]:Objective to evaluate the changes of left ventricular systolic function in patients with type 2 diabetes mellitus and impaired glucose tolerance by stratified strain technique. Methods 38 patients with type 2 diabetes mellitus with impaired glucose tolerance and 36 normal controls were enrolled in this study. Routine echocardiography was performed. Two dimensional dynamic images were stored and recorded on EchoPAC workstation, and the 18 segments of left ventricular wall were obtained. The peak circumferential strain of the middle and outer myocardium, the peak longitudinal strain of the systolic phase (LPSs), and the global delamination and whole layer strain values. There were significant differences in the outer layer and the whole layer of CS among the three groups (P 0.05). In the whole, there was a significant difference between the middle layer and the whole LPS among the three groups (P 0.05). There was no significant difference in the total outer layer LPS among the three groups (P 0.05), while in the basal segment, there was no significant difference between the three groups (P 0.05), while in the basal segment, there was no significant difference between the three groups (P 0.05). The differences of outer, middle, middle, and outer CS among the three groups were statistically significant (P 0.05), in the basal segment, in the middle, in the outer layer, in the middle segment, in the middle segment, in the middle segment, in the middle segment, and in the middle segment. There was significant difference in middle LPS between the three groups (P 0.05), but there was no significant difference between the three layers of myocardial LPS in the apical segment and the middle and outer myocardium. Conclusion the stratified strain technique can be used to quantitatively evaluate diabetes mellitus and glucose tolerance. Changes in systolic function of the left ventricular layers and the whole myocardium in normal patients, It has some clinical value in evaluating the early changes of left ventricle in patients with diabetes mellitus and impaired glucose tolerance.
【作者单位】：河南省人民医院超声科;
【基金】：国家卫生计生委2013-2014年度国家重点专科建设项目资助
【分类号】：R540.45;R587.2

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