原发性高血压患者踝臂指数、肱踝脉搏波传导速度与心脏结构、功能改变的相关性

发布时间：2018-03-24 02:14

本文选题：高血压　切入点：踝臂指数　出处：《中国动脉硬化杂志》2015年09期

【摘要】：目的探讨原发性高血压患者踝臂指数(ABI)、肱踝脉搏波传导速度(Ba PWV)与心脏结构、功能改变的相关性。方法收集新疆医科大学第一附属医院干部病房内二科2013年8月~2014年10月符合入选标准的151例高血压患者,询问病史、体检、测血压并进行全自动动脉硬化测试仪(VP-1000)和超声心动图检查及生物化学检测,分别按ABI和Ba PWV分两组:ABI低值组和ABI正常组,Ba PWV增高组和Ba PWV正常组。结果 (1)ABI低值组室间隔厚度(IVST)明显大于ABI正常组(P0.05)。与ABI正常组比较,ABI低值组左心室射血分数(LVEF)、A峰、E峰流速比值(E/A)均明显减低(P0.05)。Ba PWV增高组左心房前后径(LAD)、IVST明显大于Ba PWV正常组(P0.05)。Ba PWV增高组LVEF小于Ba PWV正常组(P0.05)。(2)相关分析显示,ABI与IVST呈负相关(r=-0.769,P0.05),与LVEF、E/A呈正相关(r值分别为0.668、0.566,P0.05)。Ba PWV与LAD、IVST呈正相关(r值分别为0.331、0.474,P0.05),与LVEF呈负相关(r=-0.526,P0.05)。结论 ABI和Ba PWV与原发性高血压患者心脏结构、功能改变呈显著相关,可为临床医生进行尽早干预治疗提供信息。
[Abstract]:Objective to investigate the relationship between the ankle brachial index (ABIV), brachial pulse wave conduction velocity (BAPWV) and cardiac structure in patients with essential hypertension. Methods 151 patients with hypertension from August 2013 to October 2014 in cadre wards of the first affiliated Hospital of Xinjiang Medical University were collected and asked for medical history and physical examination. Blood pressure and automatic arteriosclerosis tester VP-1000), echocardiography and biochemistry, According to ABI and Ba PWV, they were divided into two groups: the low value group of ABI and the normal group of ABI, the increase group of Ba PWV and the normal group of Ba PWV. Results the ventricular septal thickness of the low value group of ABI and Ba PWV was significantly higher than that of the normal group of ABI (P 0.05). Compared with the normal group of ABI, the left ventricular ejection score of the low value group was higher than that of the normal group of ABI. The ratio of E / A) decreased significantly in the left atrial anterior and posterior diameter of left atrium in the group with increased P0.05U. Ba PWV, which was significantly higher than that in the normal group of Ba PWV. The LVEF in the group with increased P0.05 PWV was lower than that in the normal group of Ba PWV. The correlation analysis showed that there was a negative correlation between LVEF and IVST, and there was a positive correlation with LVEFEP-A. There was a positive correlation between PWV and LADIVST, and a negative correlation between ABI and LVEF. Conclusion ABI and Ba PWV are associated with cardiac structure in patients with essential hypertension. Functional changes were significantly correlated and could provide information for clinicians to intervene as early as possible.
【作者单位】：新疆医科大学第一附属医院干部病房内二科;新疆医科大学基础学院病理生理学教研室;
【分类号】：R544.1

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