药物支架和切割球囊在药物洗脱支架植入术后再狭窄中治疗效果比较

发布时间：2018-03-24 10:09

本文选题：药物洗脱支架　切入点：支架内再狭窄　出处：《首都医科大学学报》2017年03期

【摘要】：目的比较药物支架再植入和切割球囊2种方法,在药物洗脱支架植入术后再狭窄病人中的治疗效果。方法回顾分析124例药物洗脱支架内再狭窄病人,经切割球囊或药物支架再次植入治疗即刻和术后随访结果。并于治疗时及术后(6.0±1.4)个月行冠脉造影检查。结果 2组病人的年龄、性别、既往病史及介入治疗前支架内再狭窄情况比较,差异无统计学意义(P0.05)。介入治疗即刻切割球囊组与药物支架组:最小管腔直径[(2.54±0.45)mm vs(2.67±0.48)mm]及直径狭窄率(23.5%±10.3%vs 21.8%±9.4%)比较,差异无统计学意义(P0.05)。术后6个月药物支架组的最小管腔直径(1.86±0.63)mm明显高于切割球囊组(1.34±0.71)mm(P0.01),且直径狭窄率显著低于切割球囊组(39.2%vs 47.8%,P0.05)。药物支架组复发再狭窄和晚期管腔丢失量均低于切割球囊组[4.1%vs 9.8%,(0.52±0.48)mm vs(0.74±0.53)mm],差异有统计学意义(P0.01)。结论药物支架再植入相比于切割球囊治疗药物洗脱支架术后再狭窄,6个月后支架内再狭窄率低于切割球囊组。
[Abstract]:Objective to compare the therapeutic effects of drug stent re-implantation and balloon cutting in patients with restenosis after drug-eluting stent implantation. Methods 124 patients with restenosis in drug-eluting stents were retrospectively analyzed. The patients were followed up immediately and postoperatively by cutting balloon or drug stents. Coronary angiography was performed at the time of treatment and 6.0 卤1.4 months after operation. Results the age and sex of the patients in both groups were higher than those in the control group. There was no significant difference in restenosis of stents before interventional therapy and history. The mean diameter of minimal lumen [2.54 卤0.45)mm vs(2.67 卤0.48)mm] and stenosis rate of 23.5% 卤10.3%vs 21.8% 卤9.4% were compared between balloon group and drug stent group immediately after interventional therapy. The minimum lumen diameter of the drug stent group was 1.86 卤0.63)mm higher than that of the incision balloon group (1.34 卤0.71 mm), and the diameter stenosis rate was significantly lower than that of the incision balloon group (39.2 vs 47.8% P0.05A). The recrudescent restenosis and late lumen loss in the drug stent group were significantly lower than those in the balloon incision group. The volume loss was lower than that in the 4.1%vs 9.8G group (0.52 卤0.48)mm vs(0.74 卤0.53)mm), and the difference was statistically significant (P 0.01). Conclusion the restenosis rate in the stenting group is lower than that in the balloon cutting group after 6 months compared with that in the balloon cutting group.
【作者单位】：深圳市孙逸仙心血管医院心内科;
【基金】：深圳市科技计划项目(JCYJ20160427174723796)~~
【分类号】：R541.4

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