绝经前女性冠心病高危因素及冠脉特点

发布时间：2018-04-24 05:02

本文选题：冠心病 + 绝经前期　；参考：《中国老年学杂志》2017年22期

【摘要】：目的探讨绝经前女性高危因素与冠心病(CHD)的发病关系及冠脉造影病变特点。方法选择行冠脉造影检查术的绝经前女性114例和绝经后女性134例。根据冠脉造影结果,将绝经前女性分为CHD组48例(42.1%),年龄(44.1±4.3)岁,共有70支病变冠脉,冠脉正常组66例(57.9%),年龄(44.3±3.8)岁;绝经后女性分为CHD组76例(55%),年龄(58±4.6)岁,共有152支病变冠脉,绝经后冠脉正常组58例(45%),年龄(57±3.8)岁。分析各组临床、冠脉病变特点。结果绝经前女性CHD高血压、糖尿病的患病率明显高于冠脉正常组,绝经后女性CHD组高血压、糖尿病及血脂异常患病率显著高于绝经前女性;绝经前女性患者多为单支血管病变,绝经后女性多为双支及多支血管病变;绝经前女性冠脉病变多20 mm,绝经后女性冠脉病变多≥20 mm。绝经前女性冠脉病变以左前降支为最常见(70%)。结论高血压及糖尿病是绝经前女性CHD主要发病因素,高甘油三酯是绝经前女性CHD最佳预测因素。绝经前女性CHD患者冠脉病变以单支血管、短病变为主,病变部位多位于前降支。
[Abstract]:Objective to investigate the relationship between high risk factors of premenopausal women with coronary heart disease (CHD) and the characteristics of coronary angiography. Methods 114 premenopausal women and 134 postmenopausal women were selected for coronary angiography. According to the results of coronary angiography, the premenopausal women were divided into group CHD, 48 cases (42.1%), age (44.1 + 4.3) years, and 70 coronary artery lesions. In the normal coronary group, 66 cases (57.9%), age (44.3 + 3.8), and postmenopausal women were divided into CHD group, 76 cases (55%), age (58 + 4.6) years, 152 coronary arteries, 58 cases (45%) and age (57 + 3.8) years after menopause, and the characteristics of coronary lesions were analyzed in each group. The result of premenopausal women with CHD hypertension was significantly higher than that of coronary heart disease. In the normal group, the incidence of hypertension, diabetes and dyslipidemia in the postmenopausal women was significantly higher than that in the premenopausal women; most of the premenopausal women were single vessel lesions, and most of the postmenopausal women were double and multiple vascular lesions; 20 mm in premenopausal women with coronary lesions, and more than 20 mm. of premenopausal women with coronary lesions before menopause in premenopausal women with coronary lesions. Left anterior descending branch is the most common (70%). Conclusion hypertension and diabetes are the main factors of CHD in premenopausal women. High triglyceride is the best predictor of CHD in premenopausal women. The coronary lesions in premenopausal women with CHD are mainly single vessel, short lesion and most of the lesion location in the anterior descending branch.

【作者单位】：河南科技大学临床医学院河南科技大学第一附属医院河南科技大学心血管病研究所;
【分类号】：R541.4

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