频发室性早搏的临床特征及其意义
发布时间：2018-05-06 00:14
本文选题：室性早搏 + 特征 ； 参考：《江苏大学》2017年硕士论文
【摘要】：一、目的室性早搏(PVC)是临床上最常见的心律失常,但目前国内关于其流行及特征等研究尚少;本研究主要对江苏大学附属医院心内科频发室性早搏患者的症状特点及心电图特征进行统计和分析。二、方法对2014年1月—2015年12月期间在江苏大学附属医院心血管内科就诊患者行12导联心电图、24小时动态心电图监测;筛选出符合条件的频发室性早搏患者,收集其心脏多普勒数据、一般临床资料和症状特征,测量患者的氮末端-脑利钠肽前体(NT-proBNP),分析频发室早患者心功能减退的相关因素。三、结果1、本研究共筛选出患者91例,平均年龄48±19岁,症状持续时间45±16月,其中心悸66例,无症状23例,晕厥2例,气短或头晕或乏力共31例;24小时PVC平均数量为(19782.5±11289.8)次,PVC平均负荷(22.5±12.7)%。2、PVC负荷及PVC-QRS波时限与LVEDD、BNP、左室流出道起源呈正相关,与LVEF呈负相关;此外,PVC负荷与男性,PVC-QRS时限与年龄、症状持续时间、PVC负荷呈正相关。3、与LVEF≥50%组相比,LVEF50%组患者的PVC-QRS波时限、症状持续时间更长及左室舒张末内径(LVEDD)、PVC负荷、PVC数量、左室流出道起源比例更大(P㩳0.05)。四、结论江苏大学附属医院心血管内科频发室早患者的检出率为1.6%,其中绝大多数患者以心悸为主要临床症状,但也有少部分患者表现为晕厥等。PVC负荷及PVC-QRS波时限与LVEDD、BNP、左室流出道起源室早、LVEF存在相关性;且PVC-QRS波时限、左室流出道起源PVC、PVC症状持续时间及男性是LVEF降低的预测因素。另外,PVC-QRS波的时限、PVC症状持续时间、PVC起源部位对治疗室早方法的选择可能有一定的临床价值。
[Abstract]:Objective: PVC (ventricular premature beat) is the most common arrhythmia in clinic, but there are few studies on its prevalence and characteristics in China. The characteristics of symptoms and electrocardiogram of patients with frequent ventricular premature beats in Department of Cardiology, affiliated Hospital of Jiangsu University were analyzed. Methods from January 2014 to December 2015, patients in the Department of Cardiovascular Medicine, affiliated Hospital of Jiangsu University, were monitored by 12-lead electrocardiogram (ECG) and 24-hour ambulatory electrocardiogram (ECG). The cardiac Doppler data, general clinical data and symptom characteristics were collected to measure the N-terminal-brain natriuretic peptide precursor NT-proBNPP, and to analyze the related factors of cardiac dysfunction in patients with frequent ventricular early onset. Results 1. 91 patients (mean age 48 卤19 years) with symptoms lasting 45 卤16 months were selected, including 66 cases of palpitation, 23 cases of asymptomatic syncope and 2 cases of syncope. In 31 cases of shortness of breath or dizziness or fatigue, the average number of PVC in 24 hours was 19782.5 卤11289.8) the average load of PVC and the duration of PVC-QRS wave were positively correlated with the origin of left ventricular outflow tract and negatively correlated with the origin of left ventricular outflow tract, and the time of PVC-QRS and the age of male PVC-QRS, and the mean load of PVC was 22. 5 卤12. 7%, and the duration of PVC-QRS wave was positively correlated with the origin of left ventricular outflow tract. Compared with LVEF 鈮，
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