老年高血压患者肠道菌群变化及其与C反应蛋白和脂代谢指标的相关性

发布时间：2018-05-12 05:17

本文选题：高血压 + 肠道菌群　；参考：《中国老年学杂志》2017年08期

【摘要】：目的探讨老年高血压患者肠道菌群变化及其与C反应蛋白(CRP)和脂代谢指标的相关性。方法选择老年高血压患者70例作为高血压组和老年健康体检者70例作为对照组,测量两组患者CRP、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、肠道菌群情况。结果高血压组TC、TG、LDL-C、HDL-C、CRP和对照组比较无明显差异(P0.05)。高血压组双歧杆菌属和多形拟杆菌低于对照组(P0.05),直肠真杆菌高于对照组(P0.05)。高血压组患者双歧杆菌属、多形拟杆菌、直肠真杆菌与CRP、TC、TG、LDL-C、HDL-C均无显著相关性(P0.05)。结论老年高血压患者双歧杆菌属和多形拟杆菌减少,肠道直肠真杆菌增加,老年高血压患者肠道菌群变化和炎症指标及脂代谢指标无明显相关性。
[Abstract]:Objective to investigate the changes of intestinal flora and its correlation with C-reactive protein (CRP) and lipid metabolism in elderly patients with hypertension. Methods 70 elderly patients with hypertension were selected as hypertension group and 70 elderly healthy persons as control group. The levels of CRP, TC, TG, LDL-C, HDL-C, and intestinal flora were measured in two groups. Results there was no significant difference in CRP between TCU and TGG LDL-CU in hypertension group and control group (P 0.05). Bifidobacterium and polymorphic bacilli in hypertension group were lower than those in control group (P 0.05A), and the rate of rectobacillus was higher than that in control group (P 0.05). In hypertension group, there was no significant correlation between Bifidobacterium, polymorphic bacilli, eutectobacillus rectum and HDL-C of TGN LDL-CU. Conclusion Bifidobacterium and polymorphic bacilli decreased in elderly patients with hypertension, while the intestinal eubacter increased. There was no significant correlation among intestinal flora, inflammatory index and lipid metabolism index in elderly patients with hypertension.
【作者单位】：宁波市第七医院镇海区人民医院综合内科;宁波市第七医院镇海区人民医院消化内科;
【分类号】：R544.1

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