老年慢性心力衰竭患者的血清铁蛋白、铁调素水平变化及临床意义

发布时间：2018-06-29 05:35

本文选题：老年人 + 慢性心力衰竭　；参考：《实用医学杂志》2017年24期

【摘要】：目的探讨血清铁蛋白(SF)、血清铁调素(Hepc)在老年慢性心力衰竭(CHF)患者中的水平变化及临床意义。方法选择2015年10月至2017年2月老年慢性心力衰竭患者80例作为心衰组,同期住院无心功能不全患者80例作为对照组。检测两组血清铁蛋白(SF)、Hepc水平并进行比较和分析。结果老年心衰组的SF、Hepc、hs-CRP分别为(69.58±27.16)ng/mL、(97.16±16.81)ng/mL、(3.35±1.64)mg/L,对照组的SF、Hepc、hs-CRP分别为(128.46±33.28)ng/mL、(54.12±15.76)ng/mL、(2.80±1.36)mg/L,差异有统计学意义(均P0.05)。慢性心力衰竭多因素Logistic回归分析,血清铁蛋白为慢性心力衰竭的保护因素(P0.05),Hepc、超敏C反应蛋白为慢性心力衰竭的独立危险因素(P0.05)。结论 SF可能是老年慢性心力衰竭的保护因素;Hepc及超敏C反应蛋白可能是老年慢性心力衰竭的危险因素。通过检测SF、Hepc、hs-CRP可早期识别老年慢性心力衰竭,有助于早期预防和治疗老年慢性心力衰竭。
[Abstract]:Objective to investigate the changes and clinical significance of serum ferritin (SF) and iron modulin (Hepc) in elderly patients with chronic heart failure (CHF). Methods 80 elderly patients with chronic heart failure from October 2015 to February 2017 were selected as heart failure group and 80 patients without cardiac insufficiency as control group. The levels of serum ferritin (SF) Hepc in the two groups were measured and compared and analyzed. Results the levels of hs-CRP in elderly patients with heart failure were (69.58 卤27.16) ng / mL, (97.16 卤16.81) ng / mL, (3.35 卤1.64) mg / L, respectively, and those in control group were (128.46 卤33.28) ng / mL, (54.12 卤15.76) ng / mL, (2.80 卤1.36) mg / mL, respectively (P0.05). Multivariate logistic regression analysis showed that serum ferritin was the protective factor of chronic heart failure (P0.05) and hypersensitive C-reactive protein was the independent risk factor of chronic heart failure (P0.05). Conclusion SF may be the protective factor of chronic heart failure in the elderly. Hepc and hypersensitive C-reactive protein may be the risk factors of chronic heart failure in the elderly. The detection of SFN Hepcfen hs-CRP can early identify the elderly chronic heart failure, which is helpful to the early prevention and treatment of elderly chronic heart failure.
【作者单位】：石河子大学医学院第一附属医院老年病学;石河子大学医学院第一附属医院老年干部保健二科;
【基金】：新疆生产建设兵团农八师师市计划项目(编号:2015YL09)
【分类号】：R541.6

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