膳食胆固醇摄入量对我国成人血压值和高血压发病影响的多水平纵向研究

发布时间：2018-07-14 19:12

【摘要】：目的分析我国成年人膳食胆固醇摄入量对血压值及高血压发病的影响。方法利用中国健康与营养调查数据,研究对象为1993-2011年至少参加两轮调查且在进入队列时血压值正常年龄18~60岁的成人,共7754(男性3756、女性3998)人。应用三水平混合效应模型进行分析:模型1,只纳入膳食胆固醇摄入量;模型2,在模型1的基础上,纳入个人水平变量;模型3,在模型2的基础上,纳入社区变量。结果与不摄入膳食胆固醇的男女性相比,膳食胆固醇摄入量最高组收缩压增加了1.87(男性,95%CI 1.01~2.73,P0.05)、1.44mm Hg(女性,95%CI0.54~2.35,P0.05);舒张压升高了2.04(男性,95%CI 1.40~2.67,P0.05)、0.82mm Hg(女性,95%CI0.21~1.44,P0.05);男性和女性发生高血压的相对危险分别是1.78(95%CI 1.29~2.45,P0.05)和1.23(95%CI0.87~1.74,P=0.25)。在调整了个体水平、社区水平、基线血压值和基线年龄后,与不摄入膳食胆固醇组相比,胆固醇摄入量与男性收缩压和舒张压呈正相关,与女性收缩压和舒张压呈负相关,男性和女性的膳食胆固醇摄入水平最高组发生高血压的相对危险分别增加,但都无统计学意义。结论无论男性还是女性,膳食胆固醇摄入对血压值和高血压发病风险可能没有影响。
[Abstract]:Objective to analyze the effect of dietary cholesterol intake on blood pressure and hypertension in Chinese adults. Methods based on the data of China Health and Nutrition Survey, 7754 subjects (male 3756, female 3998) who took part in at least two rounds of surveys from 1993 to 2011 and whose blood pressure was normal at the time of enrolling were 180-60 years old. A three-level mixed effect model was used to analyze: model 1, which included dietary cholesterol intake only; model 2, which included individual level variables on the basis of model 1; model 3, which included community variables on the basis of model 2. Results compared with men and women who did not eat dietary cholesterol, The systolic blood pressure (SBP) of the highest dietary cholesterol intake group increased by 1.87 (male 95 CI 1.01v 2.73%) 1.44 mm Hg (female 95 CI 0.54 卤2.35%), diastolic blood pressure increased 2.04 (male 9595 CI 1.40 2.67%) 0.82mm Hg (female 95CI 0.211.44), the relative risk of male and female developing hypertension were 1.78 (95CI 1.292.455) and 1.23 (95CI 0.871.744 P0.25) respectively. After adjusting for individual level, community level, baseline blood pressure and baseline age, cholesterol intake was positively correlated with systolic and diastolic blood pressure in men and negatively correlated with systolic and diastolic blood pressure in women compared with those without dietary cholesterol intake. The relative risk of hypertension was increased in the highest dietary cholesterol intake group for both men and women, but there was no statistical significance. Conclusion Dietary cholesterol intake may not affect blood pressure and hypertension risk in both men and women.
【作者单位】：中国疾病预防控制中心营养与健康所;
【基金】：中国健康与营养调查(R01-HD30880,DK056350,R01-HD38700) 达能营养中心膳食营养研究与宣教基金(DIC201302)
【分类号】：R544.1

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