心内科住院患者冠心病发病风险与缺牙数目相关性的临床研究

发布时间：2018-10-25 13:30

【摘要】：目的:探讨冠心病发病风险与牙齿缺失数目之间的相关关系。方法:选取2016年5~11月因胸痛于山西省心血管病医院心内科住院的506名患者为研究对象,对其进行统一问卷调查及口腔临床检查,记录基本信息、全身情况、口腔状况。依据纳入标准,最终纳入328例研究对象,根据冠脉造影结果,将其分为非冠心病组(主要血管管腔直径狭窄程度50%)、单支病变组、双支及以上病变组进行相关性分析。结果:单因素分析结果显示,年龄,性别,吸烟史,牙龈指数,缺牙数目差异均有统计学意义(P0.05)。ordinal logistic回归分析显示,缺牙数目为冠心病发病的主要危险因素,与无缺牙相比,缺牙数目为1~5颗时,冠心病发病风险增加83%(OR=1.825,95%CI=1.074-3.1),当缺牙数目超过5颗以上时,冠心病发病风险增加1.65倍(OR=2.65,95%CI=1.471-4.956)。结论:对于本研究的心内科住院人群,缺牙数目可能是冠心病发病风险增加的独立危险指标,并且随着牙齿缺失数目的增多,风险随之升高;随着年龄增加,风险增加;男性的风险较女性高。
[Abstract]:Objective: to investigate the relationship between the risk of coronary heart disease and the number of tooth loss. Methods: 506 patients who were hospitalized in the Department of Cardiology of Shanxi Cardiovascular Disease Hospital from May to November 2016 were selected as the research objects. The subjects were investigated with a unified questionnaire and clinical examination of stomatology to record the basic information, general situation and oral condition. According to the inclusion criteria, 328 patients were included. According to the results of coronary angiography, they were divided into non-coronary heart disease group (50% stenosis degree of main vascular lumen diameter), single vessel lesion group, double vessel disease group and above lesion group for correlation analysis. Results: univariate analysis showed that there were significant differences in age, sex, smoking history, gingival index and the number of missing teeth (P0.05). Ordinal logistic regression analysis showed that the number of missing teeth was the main risk factor of coronary heart disease, compared with no missing teeth. The risk of coronary heart disease (OR=1.825,95%CI=1.074-3.1) increased by 83% (OR=1.825,95%CI=1.074-3.1) when the number of teeth was 1 or 5, and the risk of coronary heart disease (OR=2.65,95%CI=1.471-4.956) increased by 1.65 times when the number of teeth was more than 5. Conclusion: the number of missing teeth may be an independent risk indicator for increasing the risk of coronary heart disease, and the risk increases with the increase of the number of missing teeth, and the risk increases with the increase of age. Men are at higher risk than women.
【作者单位】： 山西医科大学口腔医学系;山西省心血管病医院心内科;
【基金】：国家自然科学基金项目(编号:81271144、31050002)
【分类号】：R541.4
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