心脏磁共振电影成像在射血分数保留心力衰竭诊治中的应用

发布时间：2018-10-25 15:08

【摘要】：目的探讨心脏磁共振电影成像在评价射血分数保留心力衰竭(HFpEF)左心室舒张功能中的作用。方法应用心脏磁共振成像获取30例HFpEF患者和15例心功能正常者(对照组)的左心室长轴两腔、三腔、四腔及系列短轴电影图像,绘制左心室容积-时间曲线(VTC)及整体应变曲线,比较两组峰值充盈速率及充盈量,以及整体纵向、径向、周向峰值应变和应变率等参数。结果与对照组相比,HFpEF患者左心室重构指数(LVRI)增加(0.86±0.15vs 0.73±0.08,P0.05),舒张早、晚期峰值充盈速率比(PFR1/PFR2)降低或倒置(0.74±0.14vs 1.43±0.34,P=0.001),早期充盈量(FV1)及其占总充盈量比例降低(26.24±9.74vs 31.30±5.17,0.59±0.05vs 0.69±0.03;P均0.05),左心室整体纵向峰值应变(GLS)降低[(-14.96±1.79)%vs(-20.96±0.84)%,P0.01],整体纵向、径向、周向峰值应变率均降低(0.65±0.16vs 1.29±0.27,-2.23±0.71vs-3.80±1.13,1.02±0.14vs 1.77±0.63;P均0.05)。结论通过心脏磁共振获得的LVRI、PFR1/PFR2、FV1和整体周向峰值应变率能够较准确地反映HFpEF左心室舒张功能的改变,对于HFpEF诊治具有较高的临床价值。
[Abstract]:Objective to investigate the role of cardiac magnetic resonance imaging (Mr) in evaluating left ventricular diastolic function in patients with congestive heart failure (HFpEF). Methods Cardiac magnetic resonance imaging (Mr) was performed in 30 patients with HFpEF and 15 patients with normal cardiac function (control group). Left ventricular long axis images of two, three, four and a series of short axis films were obtained, and left ventricular volume-time curves (VTC) and global strain curves were drawn. The peak filling rate and filling rate, as well as the parameters of longitudinal, radial and circumferential peak strain and strain rate were compared between the two groups. Results compared with the control group, the left ventricular remodeling index (LVRI) in HFpEF patients increased (0.86 卤0.15vs 0.73 卤0.08p0.05), and the left ventricular remodeling index was early diastolic. 鏅氭湡宄板，

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