非高密度脂蛋白胆固醇水平与冠心病病情的相关性分析

发布时间：2018-11-02 10:28

【摘要】：目的探讨非高密度脂蛋白胆固醇水平与冠心病患者病情的相关性。方法对522例行冠状动脉造影检查的患者进行回顾性分析,根据冠状动脉造影结果结合临床特点、心电图表现、心肌标志物结果分为非冠心病组、心绞痛组、心肌梗死组,平均年龄60.00±10.02岁。采用Gensini评分评估冠心病患者冠状动脉病变程度,收集所有患者临床资料,采集静脉血检测血脂指标并计算非高密度脂蛋白胆固醇值,分析非高密度脂蛋白胆固醇水平与冠心病病情的相关性。结果三组间的非高密度脂蛋白胆固醇水平、Gensini积分差异有统计学意义(P0.05);心绞痛组非高密度脂蛋白胆固醇水平与Gensini积分正相关(r=0.130,P=0.022),心肌梗死组非高密度脂蛋白胆固醇水平与Gensini积分正相关(r=0.213,P=0.048);多元无序Logistic回归分析显示,年龄、性别、非高密度脂蛋白胆固醇水平是影响冠心病病情的危险因素(P0.05)。结论非高密度脂蛋白胆固醇水平是影响冠心病患者病情的一项重要指标。
[Abstract]:Objective to investigate the relationship between non-high density lipoprotein cholesterol and coronary heart disease. Methods 522 patients who underwent coronary angiography were retrospectively analyzed. According to the results of coronary angiography combined with clinical features, electrocardiogram (ECG), myocardial markers were divided into non-coronary heart disease group, angina pectoris group and myocardial infarction group. The average age was 60.00 卤10.02 years old. The severity of coronary artery disease was evaluated by Gensini score, clinical data of all patients were collected, blood lipids were measured and non-high density lipoprotein cholesterol (NHDL-C) was calculated. To analyze the correlation between the level of non high density lipoprotein cholesterol and the condition of coronary heart disease. Results there were significant differences in the level of non-high density lipoprotein cholesterol and Gensini score among the three groups (P0.05). There was a positive correlation between the level of non-high density lipoprotein cholesterol and Gensini score in angina pectoris group (r = 0.130 P0. 022) and Gensini score in myocardial infarction group (r = 0. 213). Multiple disordered Logistic regression analysis showed that age, sex and non-high density lipoprotein cholesterol level were the risk factors of coronary heart disease (P0.05). Conclusion non-high density lipoprotein cholesterol is an important index to affect the condition of patients with coronary heart disease.
【作者单位】：华北理工大学附属医院心内二科;唐山市开平区医院急诊科;唐山市南堡开发区医院内科;
【分类号】：R541.4

【相似文献】