急性ST段抬高型心肌梗死患者mCRP、GAS与冠状动脉病变程度相关性研究

发布时间：2018-12-17 08:48

【摘要】：目的:探讨急性ST段抬高型心肌梗死(STEMI)患者血浆单体C-反应蛋白(mCRP)水平、整体面积应变(GAS)与冠状动脉(冠脉)病变程度的相关性。方法:选取就诊于我院心内科的180例患者,分为STEMI组150例和对照组30例。其中STEMI组依据Gensini积分分为:轻度组(0积分≤40)、中度组(40积分80)和重度组(积分≥80)。分析血浆mCRP水平及左室射血分数(LVEF)值、GAS值在各组间的差异,Pearson相关分析研究mCRP水平、GAS值与Gensini积分的相关性。结果:(1)STEMI组患者血浆mCRP水平显著高于对照组(P0.05),STEMI组各亚组间差异亦有统计学意义(P0.05);STEMI组GAS值低于对照组(P0.05),各亚组间差异亦有统计学意义(P0.05)。(2)mCRP水平与Gensini积分正相关(r=0.672,P0.05),GAS值与Gensini积分呈负相关(r=-0.56,P0.05)。结论:mCRP水平、GAS与STEMI冠脉病变严重程度密切相关,提示mCRP水平联合GAS可以早期、无创评估STEMI病情严重程度。
[Abstract]:Aim: to investigate the relationship between plasma C-reactive protein (mCRP) level, global area strain (GAS) and severity of coronary artery lesions in patients with acute ST segment elevation myocardial infarction (STEMI). Methods: 180 patients in cardiology were divided into STEMI group (n = 150) and control group (n = 30). According to Gensini score, STEMI group was divided into mild group (0 integral 鈮，

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