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应用血流向量成像技术研究原发性高血压左室能量损耗

发布时间:2019-03-12 11:08
【摘要】:本研究旨在运用血流向量成像技术(VFM)研究原发性高血压患者左心室能量损耗差异,尽早检出流场力学异常的高血压患者,早期预防靶器官损害,并初步探索反映原发性高血压患者心脏舒缩功能变化的新方法。纳入健康志愿者22例、左室心肌质量指数(LVMI)正常的高血压患者14例及LVMI升高的高血压患者21例作为研究对象,分别行常规超声心动图、VFM检查及双频脉冲多普勒检查。结果显示高血压病例组的左室能量损耗明显高于正常组(P0.05),且舒张期能量损耗=0.439×SBP(收缩压) 8.349,收缩期能量损耗=0.385×SBP+0.644×LVMI 10.854;左室舒缩期能量损耗与E/e'相关,但与左室射血分数(EF)不相关。研究表明左室能量损耗有助于发现高血压患者流场力学变化;左室能量损耗变化是否能成为评估左室舒张功能的新指标,尚需深入研究;SBP是舒张期能量损耗的独立预测因素,LVMI及SBP是收缩期能量损耗的独立预测因素。
[Abstract]:The aim of this study was to study the difference of left ventricular energy loss in patients with essential hypertension by using the blood flow vector imaging technique (VFM), to check out the hypertension patients with abnormal flow field mechanics as early as possible, and to prevent the damage of target organs in the early stage. In this paper, a new method to reflect the changes of the systolic function of the heart in patients with essential hypertension is explored. 22 patients with healthy volunteers,14 patients with normal left ventricular mass index (LVMI) and 21 patients with high blood pressure (LVMI) were treated as subjects, with routine echocardiography, VFM and dual-frequency pulse Doppler. 缁撴灉鏄剧ず楂樿鍘嬬梾渚嬬粍鐨勫乏瀹よ兘閲忔崯鑰楁槑鏄鹃珮浜庢甯哥粍(P0.05),涓旇垝寮犳湡鑳介噺鎹熻,

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