介入造影定位法制作比格犬卵圆孔未闭模型

发布时间：2018-02-15 03:55

本文关键词： 犬卵圆孔未闭穿刺术介入　出处：《介入放射学杂志》2016年05期 　论文类型：期刊论文

【摘要】：目的介绍一种用于制作比格犬卵圆孔未闭(PFO)模型的介入造影定位穿刺方法。方法15只健康比格犬通过介入造影定位法制作PFO模型。全身麻醉下穿刺右股静脉,在右前斜30°X线投照角度下,于上腔静脉边推对比剂边回撤导管至右房底部作造影,结合改良右心房造影穿刺(Inoue法)定位法作房间隔穿刺,用14 F扩张鞘管扩张房间隔,制作犬PFO模型。结果与犬房间隔穿刺相关生理与解剖:静息心率快,左右心房内径小,伴有奇静脉开放,下腔静脉在右心房开口位置高,下腔静脉长轴与其入右心房口处均有明显成角,且与房间隔平面成角大。15只比格犬右股静脉穿刺成功率为100%;14只犬房间隔穿刺成功,且均制成PFO模型,1只犬穿破心包放弃进一步操作,成功率为93.3%(14/15);PFO模型制成后即刻超声测量显示,PFO大小为2.5~4.1(3.2±0.7)mm。结论介入造影定位法制作比格犬PFO模型,操作简便、安全,成功率高。
[Abstract]:Objective to introduce an interventional radiographic puncture method for making the model of PFOO in Beagle dogs. Methods Fifteen healthy Beagle dogs were used to make PFO model by interventional radiography, and the right femoral vein was punctured under general anesthesia. At the angle of 30 掳X ray of right anterior oblique, the catheter was removed from the superior vena cava to the bottom of the right atrium while pushing contrast agent, and the atrial septum was punctured with the modified right atrial angiography puncture (Inoue method). The atrial septum was dilated with 14 F dilated sheath tube, and the atrial septum was dilated with 14 F dilated sheath tube. Results: the resting heart rate was fast, the diameter of left and right atrium was small, the azygos vein was open, and the inferior vena cava was high in the right atrial opening. The long axis of inferior vena cava and its entering right atrial orifice were obviously angled, and the success rate of right femoral vein puncture in 15 Beagle dogs with large angle to atrial septal plane was 100% and 14 dogs were successful. All of them were made into PFO model and 1 dog gave up further operation after pericardial perforation, and the success rate was 93.314 / 15 / 15. The ultrasonic measurement showed that the size of PFO was 2.5 卤4.1 卤0.7 mm.Conclusion it is simple, safe and successful to make the PFO model of Beagle dog by interventional localization.
【作者单位】：沈阳军区总医院先心病内科;沈阳军区总医院实验动物科;
【基金】：国家自然科学基金面上项目(81370276)
【分类号】：R541.1;R-332

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