静电纺丝法制备载银敷料及其性能表征

发布时间：2018-02-24 00:45

  本文关键词： 静电纺丝 壳聚糖 聚乳酸 聚己内酯 敷料 银　出处：《化工新型材料》2017年04期 　论文类型：期刊论文

【摘要】：采用静电纺丝方法制备了聚乳酸(PLA)/聚己内酯(PCL)-聚乙烯醇(PVA)-壳聚糖(CS)-银(Ag)抗菌剂纳米纤维敷料。通过扫描电镜观察了纤维的微观结构,同时对其亲水性能及抗菌性进行了测试,结果表明,通过使用甲酸/丙酮作为CS的溶剂,同时添加PVA改善CS和PLA/PCL的相容性,能够获得直径均匀的纳米纤维,其静态接触角大幅度降低,吸水性、保水性和水汽透过率有显著的提高。当银抗菌剂的质量分数在0.125‰时,敷料对于革兰氏阳性菌金黄色葡萄球菌和革兰氏阴性菌大肠杆菌具有良好的抗菌活性,可用于制备创面抗菌敷料。
[Abstract]:Poly (lactic acid) PLAN / poly (caprolactone) / polyvinyl alcohol (PVA) -polyvinyl alcohol (PVA) -polyvinyl alcohol (PVA) -chitosan (CSA) -AgAg-based antibacterial nano-fiber dressings were prepared by electrospinning method. The microstructure of the fibers was observed by scanning electron microscope (SEM), and the hydrophilic and antibacterial properties of the fibers were tested. The results show that by using formic acid / acetone as the solvent of CS and adding PVA to improve the compatibility of CS and PLA/PCL, the uniform diameter nanofibers can be obtained. When the mass fraction of silver antibacterial agent was 0.125 鈥，

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