国人距状沟形态、大小及侧差、性差的MRI研究

发布时间：2018-03-11 03:06

本文选题：距状沟　切入点：MRI　出处：《山东大学》2010年硕士论文　论文类型：学位论文

【摘要】： 距状沟是枕叶内侧面较为重要和恒定的脑沟,是临床疾病诊断、手术治疗及功能研究的界标性结构。但对距状沟形态、大小、侧差及性差的活体影像学研究资料较为缺乏。本研究对60例(男30,女30)健康青年志愿者的头部MRI图像进行三维重建后,观察距状沟后部在正中矢状面上的形态、位置,并分析其左右侧差和男女性差别。同时研究了枕叶副脑室的出现率。用Brainvisa软件对获取的MR图像进行三维重建后,软件自动测量距状沟的沟深、沟宽和沟长。用SPSS软件对结果进行统计分析,比较左右侧的差别及男女性的差别。本研究对活体的MRI图像进行三维重建后研究距状沟的形态、大小及侧差和性差,为枕叶病变诊断、枕叶手术及视觉皮质功能影像学研究提供解剖学基础。本实验分为三个部分,摘要如下：第一部分国人女性距状沟形态、大小及侧差的NRI研究目的：归纳国人女性距状沟在MR图像的正常形态,提供其大小的正常值范围,并研究其左右侧的差别,为临床诊断、手术治疗和功能研究提供解剖学基础。方法：对30例女性志愿者头部进行高分辨率MRI扫描,获取横断面图像,用Brainvisa软件对其三维重建后,观察距状沟在正中矢状面上的形态和位置,软件自动测量距状沟的沟深、沟宽和沟长。用SPSS软件对结果进行统计分析,比较左右侧的差别。结果：在正中矢状面上距状沟后部分为分叉型(43.33%)和不分叉型(56.67%)。不分叉型又分为五种亚型：单峰型(16.67%)、平坦型(15.00%)、S型(10.00%)、双峰型(8.33%)和其他型(6.67%)。距状沟后部在正中矢状面上的位置可分为偏下(61.67%)、中间(30.00%)、偏上(8.33%)三种情况。枕叶副脑室的出现率为38.33%。原始数据组女性距状沟沟深右侧明显大于左侧(P＜0.001),沟宽和沟长差别无统计学意义。标准化处理组其相关参数未见有明显的左右侧差别。距状沟末端超过半数(56.67%)转到大脑半球的外侧面或底面。结论：女性距状沟的沟深右侧明显大于左侧。三维重建的研究方法在研究结构复杂的距状沟的形态和参数方面有一定的优势。第二部分国人男性距状沟的形态、大小及侧差MRI研究目的：归纳国人男性距状沟在MR图像的正常形态,提供其大小的正常值范围,并研究其左右侧差别,为临床诊断、手术治疗和功能研究提供解剖学基础。方法：对30例男性志愿者头部进行高分辨率MRI扫描,获取横断面图像,用Brainvisa软件对其三维重建后,观察距状沟在正中矢状面上的形态和位置,软件自动测量距状沟的沟深、沟宽和沟长。用SPSS软件对结果进行统计分析,比较左右侧的差别。结果：在正中矢状面上距状沟后部分为分叉型(46.67%)和不分叉型(53.33%)。不分叉型又分为五种亚型：单峰型(11.67%)、平坦型(16.67%)、S型(10.00%)、双峰型(10.00%)和其它型(5.00%)六种类型。距状沟后部在正中矢状面上的位置可分为偏下(70.00%)、中间(21.67%)、偏上(8.33%)三种情况。原始数据组及标准化处理组男性距状沟的沟底长、沟顶长、沟深和沟宽均未见明显的左右侧差别。距状沟末端超过半数(53.33%)转到大脑半球的外侧面。枕叶副脑室的出现率为36.67%。结论：男性距状沟的沟底长、沟顶长、沟深和沟宽均未见明显的左右侧差别。三维重建的研究方法在研究结构复杂的距状沟的形态和参数方面有一定的优势。第三部分国人距状沟形态及大小的男女差别目的：研究国人距状沟形态及大小的男女性差,为相应的功能研究及临床疾病研究提供解剖学基础。方法：对30例男性、30例女性志愿者头部进行高分辨率MRI扫描,获取横断面图像,用Brainvisa软件对其三维重建后,观察距状沟在正中矢状面上的形态和位置,软件自动测量距状沟的沟深、沟宽和沟长。用SPSS软件对结果进行统计分析,比较男女性差别。结果：距状沟各形态、位置分型均未见显著的男女性差别。未标化的原始数据显示男性距状沟的沟长、沟宽和沟深均稍大于女性,只有左侧沟深的差别具有统计学意义,男性明显大于女性(t=3.06,P=0.003)。数据标准化后,距状沟的相关参数均未见显著的性差。结论：原始数据组测得左侧沟深男性明显大于女性,标准化处理后此差别消失,男女性颅的大小可能是影响其距状沟大小差别的主要因素。结论和意义本研究对MRI图像进行三维重建后研究了距状沟的大小、形态以及侧差和性差的影响,为该区临床疾病诊断准确定位到脑沟水平、手术治疗中准确寻找病灶及视觉皮质功能研究提供解剖学基础和指导。与标本研究相比,本活体研究可能对临床更有指导意义。但是由于本研究志愿者的年龄范围较窄,未得到距状沟的形态特征等随年龄的变化。而且,距状沟的不同形态和大小是否与视觉功能之间有联系,也有待于进一步的研究。
[Abstract]:The calcarine sulcus is the medial occipital lobe is more important and constant, is the clinical diagnosis, treatment and functional structure of the landmark operation. But the calcarine sulcus morphology, size, poor and poor side in vivo imaging studies are lack of. This study of 60 patients (male 30, female 30) head MRI images of healthy young volunteers were reconstructed after the observation of calcarine sulcus posterior in the median sagittal plane shape, position, and analyze the difference and the difference between left and right side of men and women. At the same time on the emergence of the accessory occipital ventricle rate. 3D reconstruction of MR images with Brainvisa software software, the automatic measurement of calcarine sulcus depth, gully width and length. The results were analyzed by SPSS software. The difference between left and right side and the gap between the sexes. The calcarine sulcus forms the study MRI image in vivo three-dimensional reconstruction, the size and lateral difference and difference This study provides the anatomical basis for the diagnosis of occipital lobe lesions, occipital lobe surgery and visual cortex functional imaging. This experiment is divided into three parts, which are as follows:
The NRI study of the shape, size and side difference of female ditches in the first part of Chinese women
Objective: To summarize the normal morphology of Chinese female ditches in MR images, provide the normal range of their size, and study the difference between the left and right sides, so as to provide anatomical basis for clinical diagnosis, surgical treatment and functional research.
Methods: high resolution MRI scan in 30 cases of female volunteers head, obtain cross-sectional images, using Brainvisa software for the 3D reconstruction, observe the morphology and position of the calcarine sulcus in the sagittal plane, the software of automatic measurement of calcarine sulcus depth, gully width and length. The results were analyzed by SPSS software, comparison of left and right side of the difference.
Results: the calcarine sulcus on sagittal plane on the rear part is a bifurcation type (43.33%) and (56.67%). This type of bifurcation type is divided into five subtypes: single peak type (16.67%), flat type (15%), S (10%), Shuangfeng (8.33%) and other type. (6.67%). In the middle of the calcarine sulcus posterior sagittal position can be divided into lower (61.67%), middle (30%), partial (8.33%) three cases. Occipital ventricle vice rate of 38.33%. original data group of female calcarine sulcus was significantly larger than the left on the right side of the trench depth (P < 0.001), gully width and length of the difference was not statistically significant. The standardized treatment of left and right side group showed no obvious difference from the relevant parameters. More than half of groove end (56.67%) to the outer side of the cerebral hemisphere or the bottom surface.
Conclusion: the right side of the grooves is larger than the left side of the female grooves. The method of three-dimensional reconstruction has certain advantages in studying the morphology and parameters of the complex structures.
MRI study on the shape, size and side difference of the second parts of Chinese male ditches
Objective: To summarize the normal morphology of male male ditches in MR images, provide the normal range of their size, and study the difference between the left and right sides, so as to provide anatomical basis for clinical diagnosis, surgical treatment and functional research.
Methods: high resolution MRI scan in 30 cases of male volunteers head, obtain cross-sectional images, using Brainvisa software for the 3D reconstruction, observe the morphology and position of the calcarine sulcus in the sagittal plane, the software of automatic measurement of calcarine sulcus depth, gully width and length. The results were analyzed by SPSS software, comparison of left and right side of the difference.
Results: the calcarine sulcus on sagittal plane on the rear part is a bifurcation type (46.67%) and (53.33%). This type of bifurcation type is divided into five subtypes: single peak type (11.67%), flat type (16.67%), S (10%), Shuangfeng (10%) and other type (5%) six types. In the calcarine sulcus posterior median sagittal position can be divided into lower (70%), middle (21.67%), partial (8.33%) three cases. The original data standardization group and treatment group male calcarine sulcus of the bottom, top long ditch, ditch deep and wide ditch showed no obvious difference from the left and right sides. More than half of the end groove (53.33%) to the outer side of the cerebral hemisphere. The occipital side ventricle rate is 36.67%.
Conclusion: there is no obvious difference between the left and right sides of the furrow base, the length of the furrow, the depth of the furrow and the width of the furrow. The method of three-dimensional reconstruction has certain advantages in studying the morphology and parameters of the complex trapdoor sulcus.
The difference between the shape and size of the third parts of the national human distance trench
Objective: To study the difference in the morphology and size of human distance trench, and to provide the anatomical basis for the study of the corresponding function and the study of clinical diseases.
Methods: 30 cases of male, high resolution MRI scan was performed in 30 cases of female volunteers head, obtain cross-sectional images, using Brainvisa software for the 3D reconstruction, observe the morphology and position of the calcarine sulcus in the sagittal plane, the software of automatic measurement of calcarine sulcus depth, gully width and length of the statistical analysis. The results were compared with SPSS software, and the difference.
Results: the morphology of the calcarine sulcus, the location type of men and women. There were no significant differences of unlabeled raw data showed that male calcarine sulcus length, gully width and depth are slightly larger than females, with statistical significance only on the left side ditch deep differences, males were significantly larger than females (t=3.06, P=0.003). After data standardization, the relevant parameters of the calcarine sulcus showed no significant difference.
Conclusion: in the original data set, the left groin depth was significantly larger in males than in females. After normalization treatment, the difference disappeared. The size of male and female cranium may be the main factor affecting the size difference between them.
Conclusion and significance
The study on 3D reconstruction of MRI images of the calcarine sulcus size, shape and side effects of poor and poor, for the clinical diagnosis of disease accurately locate the cerebral sulci level, surgical treatment of lesions and accurately find visual cortical function and provide anatomical basis and guidance. This study compared with specimens. In vivo study on clinical significance. But more because the volunteers age range is narrow, not of the calcarine sulcus morphology changes with age. Moreover, calcarine sulcus of different shape and size and whether there is a link between the visual function, but also need to be further studied.

【学位授予单位】：山东大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R322.81

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