不同回波时间对扩散加权成像人脑体素不相干运动参数的影响

发布时间：2018-12-14 20:04

【摘要】：目的探讨不同回波时间(TE)对DWI人脑体素不相干运动(IVIM)参数的影响。方法对14名健康志愿者行多b值磁共振扩散加权成像(MB-DWI),采用0~1000 s/mm~2共16个b值,TE分别为65、85、105 ms,经双指数模型处理后获得f、D*及D参数图,测量双侧尾状核头、壳核和半卵圆中心的f、D*和D值,并进行统计学分析。结果随着TE的增加,基底核区灰质核团信号逐渐减低,半卵圆中心白质信号增强。尾状核头、壳核及半卵圆中心的f值逐渐升高(P均0.001);尾状核头及壳核的D*值逐渐减低(P均0.05),半卵圆中心D*值的差异无统计学意义(P0.05)。不同TE时,尾状核头、壳核及半卵圆中心的D值差异均无统计学意义(P均0.05)。相同TE时,尾状核头、壳核及半卵圆中心的D值依次减低(P均0.001)。结论 TE对f值和D*值影响较大,而对D值影响较小,针对不同的脑组织选择合适的TE可获得更准确的IVIM参数。
[Abstract]:Objective to investigate the effect of different echo time (TE) on (IVIM) parameters of DWI human brain incoherent motion. Methods Multi-b magnetic resonance diffusion weighted imaging (MB-DWI) was performed in 14 healthy volunteers, and 16 b values were obtained by using 0 1 000 s/mm~2. The TE values were 65 ms, and 85 105 ms, respectively. After double exponential model processing, fen D* and D parameter maps were obtained. The F D * and D values of bilateral caudate head, putamen and half oval center were measured and statistically analyzed. Results with the increase of TE, the signal of gray matter in basal nucleus decreased gradually, and the signal of white matter in the center of semiovale was enhanced. The f value of caudate head, putamen nucleus and centrum of semiovale increased gradually (P 0.001), and the D * value of caudate head and putamen decreased gradually (P 0.05), but there was no significant difference in D * value of center of semiovale (P0.05). There was no significant difference in D values of caudate head, putamen nucleus and semicircular center in different TE (all P 0. 05). The D values of caudate head, putamen nucleus and semioval center decreased in turn at the same TE (all P 0.001). Conclusion TE has great influence on f and D * values, but less on D value. More accurate IVIM parameters can be obtained by selecting appropriate TE for different brain tissues.
【作者单位】：南京军区南京总医院医学影像科;徐州医学院研究生学院;
【分类号】：R322.81;R445.2

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